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The small urinary extracellular vesicle proteome during renal transplantation – changing proteomic profiles from donor to one year after transplantation

Fabian Braun, Markus Rinschen, Denise Buchner, Katrin Bohl, Ingo Plagmann, Daniel Bachurski, Martin Späth, Philipp Antczak, Heike Göbel, Corinna Klein, Jan-Wilm Lackmann, Oliver Kretz, Victor G. Puelles, Roger Wahba, Michael Hallek, Bernhard Schermer, Thomas Benzing, Tobias B. Huber, Andreas Beyer, Dirk Stippel Christine Kurschat, Roman-Ulrich Müller


This data set represents the first atlas of the proteomic changes in small urinary extracellular vesicles (suEVs) throughout living donor renal transplantation. Using this app, you can easily browse through the data acquired by unbiased proteomic measurement of more than 1700 individual proteins detected in suEVs separated through differential (ultra-)centrifugation of 22 renal allograft recipients and their corresponding donors, ranging from one day before (A) to directly after (B) one day after (C) approximately 1 month after (D) and one year after transplantation. Please see tab “LFQs” to check for the mean LFQ and rank of your protein of interest as measured in the separated suEVs at timepoint A. Tab “Boxplots” enables you to display the mean LFQs per protein per timepoint in the separated suEVs throughout the course of living donor kidney transplantation.

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This site enables you to display single protein mean LFQs and according ranks as detected in the suEV proteome in the donor ("healthy control") sample one day before transplantation (Timepoint A). Please select "Mark one protein" in the upper drop down menu and your protein of interest in the lower drop down menu. To display a panel of EV marker proteins, select "Mark EV marker proteins" in the upper drop down menu.

To download the corresponding data table, please click on the icon "download data table".

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This site enables you to display the mean LFQs per protein per timepoint in the separated suEVs throughout the course of living donor kidney transplantation. Please select your protein of interest in the drop down menu.

To download the corresponding data table, please click on the icon "download data table”.